Thursday, December 22, 2011

NEW WORLD RECORD FOR SMALLEST WOMAN

Also, Learn About Brooke Greenberg; She Doesn't Age!

On December 16th, Jyoti Amge celebrated her 18th birthday and made it into the Guinness World Records as the shortest living woman. She is just 62.8 cm or 24.7 in tall. From Nagpur, India, Jyoti beat out American Bridgette Jordan who stands at 69 cm (27.2 in). But the shortest living human is a man, Junrey Balawing of the Philippines, who is 59.9 cm (23.6 in) tall. And the shortest verified human who ever lived was Gul Mohammed of India (1957 - 1997), who stood at only 57 cm (22.4 in).


~ Guinness World Records

Jyoti Amge has a condition called Achondroplasia. It is a sporadic mutation (in 85% of the cases), but it can also be inherited. According to Evolutionary Theory, genetic variation is the building block of natural selection, which gives our world a variety of life forms. It is created when there is a mutation – a change in the chemical composition of the genes. Mild variations occur most of the time and dramatic variations occur infrequently – but statistically, they must occur to somebody. While dramatic mutations tend to be detrimental to the health of the person affected, sometimes it can be beneficial to the subject or to society.


~ World's oldest stockbroker (2010)

One happy example is the world's oldest stockbroker, Irving Kahn, who turned 106 years old on December 19th. He is in great shape mentally and physically and still goes to work everyday to his high-stress job. Apparently, Irving and his siblings (who are also centenarians) possess a mutation in a gene that increases their good cholesterol (HDL) while decreasing their bad cholesterol (LDL); this and other genetic factors help to protect them from heart disease, Alzheimer's, and other age-related illnesses. Irving is involved in a study at the Albert Einstein College of Medicine's Institute for Aging Research. However, Irving is still a kid in the world of longevity. The oldest living human is Besse Cooper of the U.S. at 115 years old. And the oldest verified human who ever lived was Jeanne Calment of France at 122 years of age (1875 - 1997). Still, research into Mr. Kahn's mutation may shine some light on the Fountain of Youth to benefit mankind.


~ The Fountain of Youth? (2009)

But the most interesting is the curious case of Brooke Greenberg. She will be 19 years old on January 8th. But she hasn’t changed since she was a toddler. To this day, she is approximately 76 cm (30 in) tall and weighs around 16 pounds. Also, she has the mental capacity of a toddler. However, unlike in the case of Jyoti Amge, Brooke does not have Achondroplasia and her doctors couldn't find anything wrong with her. Her condition is called Syndrome X. One fascinating question which boggles the Frog Blog is that if Brooke's condition persists, does that mean she will never die?

Regardless, genetic mutation might have given rise to the human species. The MYH16 gene encodes the protein myosin, which regulates the powerful jaw muscles in non-human primates such as chimpanzees and gorillas. But a mutation of the MYH16 gene in early humans had caused the myosin protein to not function properly, giving humans weak jaw muscles. A controversial theory claims that because of the reduced pressure from the weaker jaw muscles of the early humans, the plates in our skulls were not forced to firm up as quickly as other primates after birth, thereby allowing our brains to grow for a longer period – increasing in size.


~ A mutuation and our big brains.

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